Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(Cyclohexen-1-yl)-1-nitrobenzene → 3-Cyclohexylbenzenamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(Cyclohexen-1-yl)-1-nitrobenzene | HCID 22019642 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-Cyclohexylbenzenamine | HCID 11321261 | 78.9% |
반응 단계
3-(Cyclohexen-1-yl)-1-nitrobenzene(7.5 g) is dissolved in ethanol (150 ml), and thereto is added 10% palladium on carbon (750 mg), and the mixture is subjected to catalytic hydrogenation at 25° C. The catalyst is removed by filtration, and the solvent is evaporated under reduced pressure. The residue is purified by silica gel column chromatography (eluent: gradient from 0% to 100% hexane/ethyl acetate) to give the desired compound (5.1 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07084176B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-12d171e79ec8486d858f0a836123bd8b |
| 출처 메모 | uspto-grants-2006_08 |