3-bromo-1-((6-isopropylpyridin-2-yl)methyl)-4-nitro-1H-indazole → 3-methyl-1-(2-(6-methylpyridin-2-yl)ethyl)-4-nitro-1H-indazole

HRID 706577노트

반응식

HRID 706577 반응식
Br[C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[N+:11]([O-:13])=[O:12])[N:4]([CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([CH3:22])[N:17]=2)[N:3]=1.Br[C:24]1C2C(=CC=CC=2[N+]([O-])=O)N(CC2C=CC=C(C(C)C)N=2)N=1>>[CH3:24][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[N+:11]([O-:13])=[O:12])[N:4]([CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([CH3:22])[N:17]=2)[N:3]=1

참가 물질

3

반응물 2

HCID 679758823-bromo-1-((6-isopropylpyridin-2-yl)methyl)-4-nitro-1H-indazoleHCID 866993283-bromo-1-(2-(6-methylpyridin-2-yl)ethyl)-4-nitro-1H-indazole

생성물 1

HCID 866993273-methyl-1-(2-(6-methylpyridin-2-yl)ethyl)-4-nitro-1H-indazole수율 83%

실험 절차

Prepared according to Preparation D, Step E, substituting 3-bromo-1-(2-(6-methylpyridin-2-yl)ethyl)-4-nitro-1H-indazole for), 3-bromo-1-((6-isopropylpyridin-2-yl)methyl)-4-nitro-1H-indazole, to give the title compound (83%).

후처리

  1. customPrepared
  2. customaccording to Preparation D, Step E

출처 및 근거

ORD 기록
ord-ff670a4c9ac74ffd8a02d204ad875aa0
출처 데이터셋
uspto-grants-2015_11
특허 번호
US09174981B2

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