Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chloro-3-nitrobenzenesulfonamide → 3-chloro-4-((tetrahydro-2H-pyran-4-yl)methylamino)benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chloro-3-nitrobenzenesulfonamide | HCID 7324 | — |
| 반응물 | N,N,N',N'-Tetramethylethylenediamine | HCID 8037 | — |
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 반응물 | 4-Methylpiperazin-1-ylamine dihydrochloride hydrate | HCID 198221 | — |
| 반응물 | 4-Aminomethyltetrahydropyran | HCID 2773210 | — |
| 생성물 | 3-chloro-4-((tetrahydro-2H-pyran-4-yl)methylamino)benzenesulfonamide | HCID 67126616 | — |
반응 단계
The title compound was prepared by substituting 4-fluoro-3-chlorobenzenesulfonamide for 4-chloro-3-nitrobenzenesulfonamide, (tetrahydro-2H-pyran-4-yl)methanamine for 4-methylpiperazin-1-amine dihydrochloride and Hunig's base for N1,N1,N2,N2-tetramethylethane-1,2-diamine in EXAMPLE 6A.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09174982B2 |
| 출처 데이터셋 | uspto-grants-2015_11 |
| ORD ID | ord-0ab115c41266436d864e6e073f2a2dad |
| 출처 메모 | uspto-grants-2015_11 |