alpha-Bromo-o-chlorotoluene → 5-[(2-Chlorobenzyl)sulfanyl]-2,3-dimethoxypyridine

반응식

Cl[C:2]1[CH:3]=[C:4]([CH:17]=[CH:18][CH:19]=1)[CH2:5][S:6][C:7]1[CH:8]=[C:9]([O:15][CH3:16])[C:10]([O:13][CH3:14])=[N:11][CH:12]=1.BrCC1C=CC=CC=1[Cl:28]>>[Cl:28][C:17]1[CH:18]=[CH:19][CH:2]=[CH:3][C:4]=1[CH2:5][S:6][C:7]1[CH:8]=[C:9]([O:15][CH3:16])[C:10]([O:13][CH3:14])=[N:11][CH:12]=1

참가 물질

반응물 2

HCID 11905alpha-Bromo-o-chlorotoluene

HCID 711858335-(3-Chlorobenzylthio)-2,3-dimethoxypyridine2회

생성물 1

HCID 711863175-[(2-Chlorobenzyl)sulfanyl]-2,3-dimethoxypyridine

실험 절차

Prepared as described for 5-(3-chlorobenzylthio)-2,3-dimethoxypyridine (Intermediate 8) but using 1-(bromomethyl)-2-chlorobenzene instead of 1-(bromomethyl)-3-chlorobenzene.

후처리

customPrepared

출처 및 근거

ORD 기록: ord-44e00ea8f847431f8af0843119147581
출처 데이터셋: uspto-grants-2015_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09180122B2

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