o-Xylyl bromide → 2,3-Dimethoxy-5-[(2-methylbenzyl)sulfanyl]pyridine

반응식

Cl[C:2]1[CH:3]=[C:4]([CH:17]=[CH:18][CH:19]=1)[CH2:5][S:6][C:7]1[CH:8]=[C:9]([O:15][CH3:16])[C:10]([O:13][CH3:14])=[N:11][CH:12]=1.Br[CH2:21]C1C=CC=CC=1C>>[CH3:14][O:13][C:10]1[C:9]([O:15][CH3:16])=[CH:8][C:7]([S:6][CH2:5][C:4]2[CH:17]=[CH:18][CH:19]=[CH:2][C:3]=2[CH3:21])=[CH:12][N:11]=1

참가 물질

반응물 2

HCID 6992o-Xylyl bromide

HCID 711858335-(3-Chlorobenzylthio)-2,3-dimethoxypyridine2회

생성물 1

HCID 711864382,3-Dimethoxy-5-[(2-methylbenzyl)sulfanyl]pyridine

실험 절차

Prepared as described for 5-(3-chlorobenzylthio)-2,3-dimethoxypyridine (Intermediate 8) but using 1-(bromomethyl)-2-methylbenzene instead of 1-(bromomethyl)-3-chlorobenzene.

후처리

customPrepared

출처 및 근거

ORD 기록: ord-2557bdb7c2e0437e9c6e43d31e913b2d
출처 데이터셋: uspto-grants-2015_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09180122B2

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