3,4-Difluorobenzyl Chloride → 5-[(3,4-Difluorobenzyl)sulfanyl]-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-one

HRID 709040

반응식

HRID 709040 반응식
C(C1C=CC(C[S:8][C:9]2[CH:10]=[C:11]([O:19][CH2:20][O:21][CH3:22])[C:12](=[O:18])[N:13]([CH2:15][O:16][CH3:17])[CH:14]=2)=CC=1)C.Cl[CH2:26][C:27]1[CH:32]=[CH:31][C:30]([F:33])=[C:29]([F:34])[CH:28]=1>>[F:34][C:29]1[CH:28]=[C:27]([CH:32]=[CH:31][C:30]=1[F:33])[CH2:26][S:8][C:9]1[CH:10]=[C:11]([O:19][CH2:20][O:21][CH3:22])[C:12](=[O:18])[N:13]([CH2:15][O:16][CH3:17])[CH:14]=1

참가 물질

3

반응물 2

HCID 27369543,4-Difluorobenzyl ChlorideHCID 867315275-[(4-ethylbenzyl)sulfanyl]-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-one2회

생성물 1

HCID 867315355-[(3,4-Difluorobenzyl)sulfanyl]-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-one

실험 절차

Prepared as described for 5-[(4-ethylbenzyl)sulfanyl]-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-one (Intermediate 17) but using 1-(chloromethyl)-3,4-difluorobenzene instead of 1-(chloromethyl)-4-ethylbenzene.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-e67300b4fa6c41f9a4098b0c8321fb7d
출처 데이터셋
uspto-grants-2015_11
특허 번호
US09180122B2

연결된 노트

불러오는 중…