5-[(3-Chloro-5-fluorobenzyl)sulfanyl]-2,3-dimethoxypyridine → 5-[(3-Chloro-5-fluorobenzyl)sulfanyl]-3-hydroxypyridin-2(1H)-one

HRID 709065노트

반응식

HRID 709065 반응식
C(SC1C=C(O)C(=O)NC=1)C1C=CC=CC=1.[Cl:17][C:18]1[CH:19]=[C:20]([CH:33]=[C:34]([F:36])[CH:35]=1)[CH2:21][S:22][C:23]1[CH:24]=[C:25]([O:31]C)[C:26]([O:29]C)=[N:27][CH:28]=1>>[Cl:17][C:18]1[CH:19]=[C:20]([CH:33]=[C:34]([F:36])[CH:35]=1)[CH2:21][S:22][C:23]1[CH:24]=[C:25]([OH:31])[C:26](=[O:29])[NH:27][CH:28]=1

참가 물질

3

반응물 2

HCID 711862245-[(3-Chloro-5-fluorobenzyl)sulfanyl]-2,3-dimethoxypyridine2회HCID 71187166HCID 71187166, 화합물

생성물 1

HCID 711872685-[(3-Chloro-5-fluorobenzyl)sulfanyl]-3-hydroxypyridin-2(1H)-one

실험 절차

Prepared as described for 5-(benzylsulfanyl)-3-hydroxypyridin-2(1H)-one (Example 1) from 5-[(3-chloro-5-fluorobenzyl)sulfanyl]-2,3-dimethoxypyridine (Intermediate 13).

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-938b3249207244a7bf1fae5048b23782
출처 데이터셋
uspto-grants-2015_11
특허 번호
US09180122B2

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