2-Ethylaniline → 5,7-Dichloro-3-methyl-1H-indazole
반응식
[Cl:1][C:2]1[CH:8]=[C:7]([Cl:9])[CH:6]=[C:5]([CH2:10][CH3:11])[C:3]=1[NH2:4].C(C1C([NH2:20])=CC=CC=1)C.ClN1C(=O)CCC1=O>C(#N)C>[Cl:9][C:7]1[CH:6]=[C:5]2[C:3](=[C:2]([Cl:1])[CH:8]=1)[NH:4][N:20]=[C:10]2[CH3:11]참가 물질
5
실험 절차
5,7-Dichloro-3-methyl-1H-indazole was prepared using a procedure similar to that described in Example 98, part a and b, except starting from 2,4-dichloro-6-ethylaniline (2.9 g) that was prepared by chlorination of 6-ethylaniline (10 g) with N-chlorosuccinimide (22 g) in acetonitrile (80 mL).
출처 및 근거
- ORD 기록
- ord-9fbb7237748140b7a07313f7f1f64687
- 출처 데이터셋
- uspto-grants-2014_09
- 특허 번호
- US08822689B2
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