Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphorus oxychloride → HCID 178490024, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | 2,4-Dimethoxyphenylpropionylchloride | HCID 15179939 | — |
| 반응물 | 1H-benzimidazole-5-carbohydrazide | HCID 16637119 | — |
| 생성물 | HCID 178490024 | HCID 178490024 | — |
반응 단계
The compound was synthesized starting from benzimidazol-5-carbohydrazide (176 mg, 1 mmol), TEA (0.153 ml; 1.1 mmol), 2,4-dimethoxyphenylpropionylchloride (228 mg, 1.1 mmol) and POCl3 (0.5 ml; 5.5 mmol) as described in method 1; yield: 0.013 mg (3.7%); MS m/z: 351.3[M+H]+; 1H-NMR (DMSO d6, 400 MHz): δ 2.97-3.00 (m, 2H); 3.11-3.13 (m, 2H); 3.71 (s, 6H); 6.41-6.43 (m, 1H); 6.51 (br s, 1H); 7.06-7.08 (m, 1H); 7.75-7.77 (m, 1H); 7.81-7.83 (m, 1H); 8.15 (br s, 1H); 8.43 (s, 1H); HPLC (METHOD [A]): rt 12.06 min (100%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09181233B2 |
| 출처 데이터셋 | uspto-grants-2015_11 |
| ORD ID | ord-97d0aada3ad847a4bd833364ed09b9ba |
| 출처 메모 | uspto-grants-2015_11 |