Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diisopropyl Ether → HCID 178511829, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diisopropyl Ether | HCID 7914 | — |
| 반응물 | P-Coumaric Acid | HCID 637542 | — |
| 반응물 | Sitagliptin | HCID 4369359 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | HCID 178511829 | HCID 178511829 | — |
반응 단계
Sitagliptin free base (0.5 gms) and coumaric acid (0.20 gms) were dissolved in methanol (3 ml) at 60° C. to 65° C. and the resultant solution was cooled to room temperature. Isopropyl ether (60 ml) was added to the resultant clear solution and stirred for 2 hours. Precipitated solids were filtered and suck dried for 20 minutes to obtain the title compound. Yield: 0.38 gms.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09181256B2 |
| 출처 데이터셋 | uspto-grants-2015_11 |
| ORD ID | ord-4e530492328c4223abc317b527971d30 |
| 출처 메모 | uspto-grants-2015_11 |