Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → (2-Methoxypyridin-4-yl)methanamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 2-Methoxyisonicotinonitrile | HCID 7204887 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | (2-Methoxypyridin-4-yl)methanamine | HCID 16227983 | — |
반응 단계
To the solution of 2-methoxyisonicotinonitrile 56-1 (1.1 g, 8.2 mmol) in methanol with 7 N NH3 was added Raney-Nickel (1.0 g). The reaction was shaken under H2 at 50 psi at room temperature in Parr shaker for 12 hours. The Raney-Nickel was removed by rotary evaporation and the filtrate was taken to dryness by rotary evaporation to give crude (2-methoxypyridin-4-yl)methanamine 56-2. MS m/z 139.2 (M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09181235B2 |
| 출처 데이터셋 | uspto-grants-2015_11 |
| ORD ID | ord-789e41ddbe0f464da7f794949dfd6c7c |
| 출처 메모 | uspto-grants-2015_11 |