2-Nitro-6-(2-(2-oxopyrrolidin-1-yl)ethoxy)benzonitrile → 2-Amino-6-(2-(2-oxopyrrolidin-1-yl)ethoxy)benzonitrile
반응식
[N+:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH2:13][CH2:14][N:15]2[CH2:19][CH2:18][CH2:17][C:16]2=[O:20])[C:5]=1[C:6]#[N:7])([O-])=O>C(O)C(F)(F)F.FC(F)(F)C(O)C(F)(F)F>[NH2:1][C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH2:13][CH2:14][N:15]2[CH2:19][CH2:18][CH2:17][C:16]2=[O:20])[C:5]=1[C:6]#[N:7]참가 물질
3
실험 절차
Prepared as in example 254b from 2-nitro-6-(2-(2-oxopyrrolidin-1-yl)ethoxy)benzonitrile (Example 257c) using trifluoroethanol/hexafluoroisopropanol (1:1) as solvent in 100% yield MS 246 (MH+).
출처 및 근거
- ORD 기록
- ord-853785370af9455a9419637d8f38e254
- 출처 데이터셋
- uspto-grants-2015_11
- 특허 번호
- US09181276B2
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