4-Bromo-3-iodopyridine → HCID 117667632, 화합물

반응식

Br[C:2]1[CH:3]=[C:4]([C:8]2[CH:9]=[C:10]3[C:15](=[N:16][CH:17]=2)[N:14]([C:18]([NH2:20])=[O:19])[CH2:13][CH2:12][CH2:11]3)[CH:5]=[N:6][CH:7]=1.[Br:21]C1C=CN=CC=1I>>[Br:21][C:3]1[CH:2]=[CH:7][N:6]=[CH:5][C:4]=1[C:8]1[CH:9]=[C:10]2[C:15](=[N:16][CH:17]=1)[N:14]([C:18]([NH2:20])=[O:19])[CH2:13][CH2:12][CH2:11]2

참가 물질

반응물 2

HCID 529111784-Bromo-3-iodopyridine

HCID 117667498HCID 117667498, 화합물

생성물 1

HCID 117667632HCID 117667632, 화합물

실험 절차

6-(4-Bromo-pyridin-3-yl)-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid amide is synthesized using the same procedures for preparing 6-(5-bromo-pyridin-3-yl)-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid amide in Example 15, replacing 3,5-dibromo-pyridine with 4-bromo-3-iodo-pyridine.

출처 및 근거

ORD 기록: ord-1abdbfd96980471cb02e7f367c5bf5f7
출처 데이터셋: uspto-grants-2015_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09181272B2

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