Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 4-[(3-Methyl-1,2,4-oxadiazol-5-yl)methoxy]aniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Sodium Dithionite | HCID 24489 | — |
| 반응물 | 3-Methyl-5-(4-nitrophenoxymethyl)-1,2,4-oxadiazole | HCID 22060445 | — |
| 생성물 | 4-[(3-Methyl-1,2,4-oxadiazol-5-yl)methoxy]aniline | HCID 22060873 | — |
반응 단계
In like manner to the preparation of 5-[(4-aminophenoxy)methyl]-3-phenyl-1,2,4-oxadiazole, 5-(4-nitrophenoxymethyl)-3-methyl-1,2,4-oxadiazole was reacted with aqueous solution of sodium hydro sulfite and K2CO3 to prepare 5-[(4-aminophenox)ymethyl]-3-methyl-1,2,4-oxadiazole. 1H NMR (CDCl3): δ 6.82 (d, 2H, J=8.8 Hz), 6.63 (d, 2H, J=8.8 Hz), 5.15 (s, 2H), 3.38 (br s, 2H), 2.41 (s, 3H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822685B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-55e235c5dabb4ca484f85939a3c24e8d |
| 출처 메모 | uspto-grants-2014_09 |