Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 5-(2,3,6-Trifluorophenyl)-3-(pyridin-3-yl)-1,2,4-oxadiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | N-Hydroxynicotinimidamide | HCID 308113 | — |
| 반응물 | 2,3,6-Trifluorobenzoic acid | HCID 520062 | — |
| 생성물 | 5-(2,3,6-Trifluorophenyl)-3-(pyridin-3-yl)-1,2,4-oxadiazole | HCID 67026104 | — |
반응 단계
The title compound was prepared according to the procedure of Example 8 using N′-hydroxynicotinimidamide (Aldrich) and 2,3,6-trifluorobenzoic acid (Aldrich). 1H NMR (300 MHz, CD3OD) δ 7.26-7.35 (m, J=9.4, 9.4, 3.8, 2.0 Hz, 1H), 7.62-7.77 (m, 2H), 8.57 (dt, J=8.0, 1.9 Hz, 1H), 8.76 (dd, J=4.8, 1.6 Hz, 1H), 9.30 (dd, J=2.4, 0.8 Hz, 1H) ppm; MS (DCl/NH3) m/z 278 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09186407B2 |
| 출처 데이터셋 | uspto-grants-2015_11 |
| ORD ID | ord-fe7eee5855eb49d3a1413bf9cfea15f2 |
| 출처 메모 | uspto-grants-2015_11 |