Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Methyl p-aminosalicylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | 4-Aminosalicylic Acid | HCID 4649 | — |
| 생성물 | Methyl p-aminosalicylate | HCID 77787 | — |
반응 단계
A solution of 4-amino-2-hydroxybenzoic acid (1 g, 6.5 mmol) in MeOH (15 mL) and concentrated sulfonic acid (1 mL) was refluxed overnight. The reaction mixture was quenched with NaHCO3 aqueous solution (60 mL) and EtOAc (60 mL). The organic layer was separated, dried, evaporated to give 3-hydroxy-4-methoxycarbonylaniline.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822685B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-aba6bdb960ce41dead32062ee1bf5d05 |
| 출처 메모 | uspto-grants-2014_09 |