1,1,2,2-Tetrafluoro-3-iodopropane → HCID 89874132, 화합물

HRID 715451

반응식

HRID 715451 반응식
[Cl:1][C:2]1[N:7]=[CH:6][C:5]([OH:8])=[C:4]([CH3:9])[CH:3]=1.[F:10][CH:11]([F:17])[C:12]([F:16])([F:15])[CH2:13]I>>[Cl:1][C:2]1[CH:3]=[C:4]([CH3:9])[C:5]([O:8][CH2:13][C:12]([F:16])([F:15])[CH:11]([F:17])[F:10])=[CH:6][N:7]=1

참가 물질

3

반응물 2

HCID 5428611,1,2,2-Tetrafluoro-3-iodopropaneHCID 712995492-Chloro-5-hydroxy-4-methylpyridine

생성물 1

HCID 89874132HCID 89874132, 화합물수율 89%

실험 절차

The title compound is prepared in 89% yield (7.97 g, pale yellow solid) from 6-chloro-4-methylpyridin-3-ol (5.00 g, 34.8 mmol) and 1,1,2,2-tetrafluoro-3-iodopropane (16.9 g, 69.7 mmol) in a similar manner to Step-1 of Amine-49.

출처 및 근거

ORD 기록
ord-899879fb78c84da8a2cee24eb07f6556
출처 데이터셋
uspto-grants-2015_11
특허 번호
US09187475B2

연결된 노트

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