Methyl chloroformate → Benzyl 4-(methoxycarbonylamino)piperidine-1-carboxylate

HRID 715590

반응식

HRID 715590 반응식
[NH2:1][CH:2]1[CH2:7][CH2:6][N:5]([C:8]([O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[O:9])[CH2:4][CH2:3]1.Cl[C:19]([O:21][CH3:22])=[O:20]>>[CH3:22][O:21][C:19]([NH:1][CH:2]1[CH2:3][CH2:4][N:5]([C:8]([O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[O:9])[CH2:6][CH2:7]1)=[O:20]

참가 물질

3

반응물 2

HCID 6586Methyl chloroformateHCID 178466404-Amino-1-N-Cbz-piperidine

생성물 1

HCID 18677680Benzyl 4-(methoxycarbonylamino)piperidine-1-carboxylate

실험 절차

The title compound is prepared from benzyl 4-aminopiperidine-1-carboxylate and methyl chloroformate following a procedure analogous to that described for Intermediate 26 Step 1. LC (method 1): tR=0.92 min; Mass spectrum (ESI+): m/z=293 [M+H]+.

출처 및 근거

ORD 기록
ord-3e08bc7cc04f4e5abdd9a6f7d3265909
출처 데이터셋
uspto-grants-2015_11
특허 번호
US09187477B2

연결된 노트

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