Octanoic hydrazide → 6-Bromo-4-hydroxy-1-methyl-N'-octanoyl-2-oxo-1,2-dihydroquinoline-3-carbohydrazide

HRID 716693

반응식

HRID 716693 반응식
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]([CH3:12])[C:7](=[O:13])[C:6]([C:14]([O:16]CC)=O)=[C:5]2[OH:19].[C:20]([NH:29][NH2:30])(=[O:28])[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]>>[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]([CH3:12])[C:7](=[O:13])[C:6]([C:14]([NH:30][NH:29][C:20](=[O:28])[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])=[O:16])=[C:5]2[OH:19]

참가 물질

3

반응물 2

HCID 80556Octanoic hydrazideHCID 90353157Ethyl 6-bromo-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate

생성물 1

HCID 715475756-Bromo-4-hydroxy-1-methyl-N'-octanoyl-2-oxo-1,2-dihydroquinoline-3-carbohydrazide

실험 절차

Reagents: Comp 35 (0.46 mmols, 0.15 g); octanoyl hydrazine (0.5 mmols, 0.08 g). Yield: 0.13 g (64%), white solid, m.p.=185° C.-186° C.

출처 및 근거

ORD 기록
ord-873bc3aa53594f939cb644226ecb692c
출처 데이터셋
uspto-grants-2015_11
특허 번호
US09193688B2

연결된 노트

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