Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(4-Fluorophenoxy)propionic acid → Dimethyl 2-(3-(4-fluorophenoxy)propanamido)malonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(4-Fluorophenoxy)propionic acid | HCID 74099 | — |
| 반응물 | Dimethyl aminomalonate hydrochloride | HCID 437601 | — |
| 생성물 | Dimethyl 2-(3-(4-fluorophenoxy)propanamido)malonate | HCID 50941576 | 80% |
반응 단계
This compound was synthesized from dimethyl aminomalonate according to the procedure for the preparation of example 2 using 3-(4-fluorophenoxy)propionic acid. The crude residue was purified by flash chromatography on silica (CH2Cl2/MeOH 50:1) to yield the title compound as a white solid (80%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09193741B2 |
| 출처 데이터셋 | uspto-grants-2015_11 |
| ORD ID | ord-8cb18608e0f94394af6f322bdd1a3d92 |
| 출처 메모 | uspto-grants-2015_11 |