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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 718957생성일: 2026년 10월 26일

2-(1-Methyl-2-((naphthalen-1-ylmethyl)carbamoyl)hydrazinyl)acetic acid → 1-(2-((S)-1-(((S)-1,1-diethoxypropan-2-yl)(naphthalen-1-ylmethyl)amino)-1,4-dioxo-4-(tritylamino)butan-2-ylamino)-2-oxoethyl)-1-methyl-4-(naphthalen-1-ylmethyl)semicarbazide

https://huagongshe.com/reaction/718957

반응식

참여 물질

역할이름HCID투입량
반응물2-(1-Methyl-2-((naphthalen-1-ylmethyl)carbamoyl)hydrazinyl)acetic acidHCID 53397539—
반응물(S)-2-amino-N1-((S)-1,1-diethoxypropan-2-yl)-N1-(naphthalen-1-ylmethyl)-N4-tritylsuccinamideHCID 67075487—
생성물1-(2-((S)-1-(((S)-1,1-diethoxypropan-2-yl)(naphthalen-1-ylmethyl)amino)-1,4-dioxo-4-(tritylamino)butan-2-ylamino)-2-oxoethyl)-1-methyl-4-(naphthalen-1-ylmethyl)semicarbazideHCID 86652585—

반응 단계

According to the procedure described in the synthesis method of Compound II-15, 2-(1-methyl-2-(naphthalen-1-ylmethylcarbamoyl)hydrazinyl)acetic acid (Compound VI-8) 67 mg (0.23 mmol) was coupled with (S)-2-amino-N1—((S)-1,1-diethoxypropan-2-yl)-N1-(naphthalen-1-ylmethyl)-N4-tritylsuccinamide (Compound IV-19) 100 mg (0.16 mmol) to obtain the title compound.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09193734B2
출처 데이터셋uspto-grants-2015_11
ORD IDord-1bc50313fa9e4a719aa45c0570079662
출처 메모uspto-grants-2015_11