HCID 21896882, 화합물 → HCID 178440011, 화합물

반응식

ClC1C=CC(C(N)C(N)CCC)=CC=1.Cl.C(OC1C=C(OC)C=CC=1C(=N)OCC)C.[Cl:32][C:33]1[CH:38]=[CH:37][C:36]([CH:39]2[NH:43][C:42]([C:44]3[CH:49]=[CH:48][C:47]([O:50][CH3:51])=[CH:46][C:45]=3[O:52][CH2:53][CH3:54])=[N:41][CH:40]2[CH2:55][CH:56]2CCC[CH2:57]2)=[CH:35][CH:34]=1>>[Cl:32][C:33]1[CH:34]=[CH:35][C:36]([CH:39]2[NH:43][C:42]([C:44]3[CH:49]=[CH:48][C:47]([O:50][CH3:51])=[CH:46][C:45]=3[O:52][CH2:53][CH3:54])=[N:41][CH:40]2[CH2:55][CH2:56][CH3:57])=[CH:37][CH:38]=1

참가 물질

반응물 3

HCID 21896882HCID 21896882, 화합물

HCID 218968861-(4-Chloro-phenyl)-pentane-1,2-diamine

HCID 1784670165-(4-chloro-phenyl)-4-cyclopentylmethyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-1H-imidazole

생성물 1

HCID 178440011HCID 178440011, 화합물

실험 절차

5-(4-Chloro-phenyl)-2-(2-ethoxy-4-methoxy-phenyl)-4-propyl-4,5-dihydro-1H-imidazole was prepared from 1-(4-chloro-phenyl)-pentane-1,2-diamine and ethyl 2-ethoxy-4-methoxy-benzimidate hydrochloride in an analogous manner as described for the preparation of 5-(4-chloro-phenyl)-4-cyclopentylmethyl-2-(2-ethoxy-4-methoxy-phenyl)-4,5-dihydro-1H-imidazole (Example 9). HR-MS (ES, m/z) observed 373.1680, calculated for C21H26N2O2Cl [(M+H)+]373.1678.