2-Amino-4-(4-methoxyphenyl)thiazole → N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-4-propylbenzenesulfonamide

HRID 719309

반응식

HRID 719309 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]=[C:11]([NH2:14])[S:12][CH:13]=2)=[CH:5][CH:4]=1.[CH2:15]([C:18]1[CH:23]=[CH:22][C:21]([S:24](Cl)(=[O:26])=[O:25])=[CH:20][CH:19]=1)[CH2:16][CH3:17]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[N:10]=[C:11]([NH:14][S:24]([C:21]3[CH:22]=[CH:23][C:18]([CH2:15][CH2:16][CH3:17])=[CH:19][CH:20]=3)(=[O:26])=[O:25])[S:12][CH:13]=2)=[CH:7][CH:8]=1

참가 물질

3

반응물 2

HCID 1596442-Amino-4-(4-methoxyphenyl)thiazoleHCID 27372224-N-Propylbenzenesulphonyl chloride

생성물 1

HCID 10157118N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-4-propylbenzenesulfonamide

실험 절차

The title compound was prepared from 4(4-methoxy-phenyl)-thiazol-2-ylamine and 4-n-propylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (32.2 mg) with purity >90%. MS (pos) m/z 389.2.

출처 및 근거

ORD 기록
ord-b9e6cd916b8b4c99a7e375dfbb6d0050
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07132436B2

연결된 노트

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