4-(2-Chlorophenyl)-1,3-thiazol-2-amine → 2,4-Dichloro-N-[4-(2-chlorophenyl)-1,3-thiazol-2-yl]-6-methylbenzenesulfonamide

HRID 719347

반응식

HRID 719347 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:9]=[C:10]([NH2:13])[S:11][CH:12]=1.[Cl:14][C:15]1[CH:20]=[C:19]([Cl:21])[CH:18]=[C:17]([CH3:22])[C:16]=1[S:23](Cl)(=[O:25])=[O:24]>>[Cl:14][C:15]1[CH:20]=[C:19]([Cl:21])[CH:18]=[C:17]([CH3:22])[C:16]=1[S:23]([NH:13][C:10]1[S:11][CH:12]=[C:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[Cl:1])[N:9]=1)(=[O:25])=[O:24]

참가 물질

3

반응물 2

HCID 2247644-(2-Chlorophenyl)-1,3-thiazol-2-amineHCID 28013872,4-Dichloro-6-methylbenzenesulfonyl chloride

생성물 1

HCID 102031902,4-Dichloro-N-[4-(2-chlorophenyl)-1,3-thiazol-2-yl]-6-methylbenzenesulfonamide

실험 절차

The title compound was prepared from 4-(2-chlorophenyl)-1,3-thiazol-2-amine and 2,4 -dichloro-6-methylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (40.3 mg) with purity >90%. MS (pos) m/z 435.0, 437.0.

출처 및 근거

ORD 기록
ord-f0bf3e2c4d634264b7f8118ef1ad0c26
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07132436B2

연결된 노트

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