반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:9]=[C:10]([NH2:13])[S:11][CH:12]=1.[Cl:14][C:15]1[S:16][C:17]([S:21](Cl)(=[O:23])=[O:22])=[CH:18][C:19]=1[Cl:20]>>[Cl:20][C:19]1[CH:18]=[C:17]([S:21]([NH:13][C:10]2[S:11][CH:12]=[C:8]([C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=3[Cl:1])[N:9]=2)(=[O:23])=[O:22])[S:16][C:15]=1[Cl:14]참가 물질
3
실험 절차
The title compound was prepared from 4-(2-chlorophenyl)-1,3-thiazol-2-amine (57 mg) and 2,3-dichlorothiophene-5-sulfonyl chloride (68 mg) as described in the synthetic METHOD B to give a white solid (56.6 mg) with purity >90%: MS (pos) m/z 425.3, 427.3; HRMS m/z 423.8737 (calc. of monoisotopic mass for C13 H7 Cl3 N2 O2 S3 gives 423.8735).
출처 및 근거
- ORD 기록
- ord-62bfaf63b74d473db71d07d3163cd4f5
- 출처 데이터셋
- uspto-grants-2006_11
- 특허 번호
- US07132436B2
연결된 노트
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