(2R)-2-isobutylsuccinic acid → HCID 86593154, 화합물
반응식
[CH2:1]([C@H:5]([CH2:9][C:10]([OH:12])=[O:11])[C:6]([OH:8])=O)[CH:2]([CH3:4])[CH3:3]>C(Cl)(=O)C>[CH2:1]([C@@H:5]1[CH2:9][C:10](=[O:11])[O:12][C:6]1=[O:8])[CH:2]([CH3:3])[CH3:4]참가 물질
3
실험 절차
A solution of (2R)-2-isobutylsuccinic acid (35 mg, 0.2 mmol) in acetyl chloride (1.2 ml) was heated at reflux under nitrogen for 2.2 hours then volatile components removed by distillation in vacuo to leave (3R)-3-isobutyldihydrofuran-2,5-dione as an oily residue which was used without further purification.
후처리
- temperatureat reflux under nitrogen for 2.2 hours
- customvolatile components removed by distillation in vacuo
출처 및 근거
- ORD 기록
- ord-fe312e0a60bb4905895e7ba0ec702844
- 출처 데이터셋
- uspto-grants-2006_11
- 특허 번호
- US07132449B2
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