Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Azobisisobutyronitrile → Ethyl 2'-bromomethyl-2-biphenylcarboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Azobisisobutyronitrile | HCID 6547 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | [1,1'-Biphenyl]-2-carboxylic acid, 2'-methyl-, ethyl ester | HCID 18325921 | — |
| 반응물 | 4'-Bromomethyl-biphenyl-3-carboxylic acid ethyl ester | HCID 21464255 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | Ethyl 2'-bromomethyl-2-biphenylcarboxylate | HCID 58610597 | — |
반응 단계
2′-Bromomethyl-biphenyl-2-carboxylic acid ethyl ester was synthesized as described for 4′-bromomethyl-biphenyl-3-carboxylic acid ethyl ester. 2′-Methyl-biphenyl-2-carboxylic acid ethyl ester (10.35 g, 43.07 mmol, 1 eq.) in carbon tetrachloride was treated with N-bromosuccinimide (9.20 g, 51.68 mmol, 1.2 eq.) and 2,2′-azobisisobutyronitrile (0.35 g, 2.15 mmol, 5 mol %). When complete, the reaction was worked up as described leaving an orange oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07132456B2 |
| 출처 데이터셋 | uspto-grants-2006_11 |
| ORD ID | ord-bfe0762c9053428d9e2d601f66ec8932 |
| 출처 메모 | uspto-grants-2006_11 |