2H-1,4-benzoxazin-3(4H)-one → 6-(6-Bromohexanoyl)-2H-1,4-benzoxazin-3(4H)-one

HRID 719772

반응식

HRID 719772 반응식
[O:1]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[NH:4][C:3](=[O:11])[CH2:2]1.[Br:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18](Cl)=[O:19]>>[Br:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]([C:9]1[CH:8]=[CH:7][C:6]2[O:1][CH2:2][C:3](=[O:11])[NH:4][C:5]=2[CH:10]=1)=[O:19]

참가 물질

3

반응물 2

HCID 727572H-1,4-benzoxazin-3(4H)-oneHCID 898486-Bromohexanoyl chloride

생성물 1

HCID 218869936-(6-Bromohexanoyl)-2H-1,4-benzoxazin-3(4H)-one수율 45.1%

실험 절차

Using 2H-1,4-benzoxazin-3(4H)-one (15.0 g) and 6-bromohexanoyl chloride (25.8 g) according to the same method as that of Reference Example 1, the title compound (14.8 g) was obtained as colorless crystals.

출처 및 근거

ORD 기록
ord-f8799234a80d499aad3e610668af8ffd
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07132547B2

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