Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Chloro-1,2,3,4-tetrahydronaphthalene → (+/-)-8-{3-[1-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4-piperidinyl]propanoyl}-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Chloro-1,2,3,4-tetrahydronaphthalene | HCID 188717 | — |
| 반응물 | 8-[3-(4-piperidinyl)propanoyl]1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one | HCID 9966544 | — |
| 생성물 | (+/-)-8-{3-[1-(1,2,3,4-Tetrahydro-1-naphthalenyl)-4-piperidinyl]propanoyl}-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one hydrochloride | HCID 21887715 | 5.6% |
반응 단계
Using 8-[3-(4-piperidinyl)propanoyl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one (500 mg) and (±)-1-chloro-1,2,3,4-tetrahydronaphthalene (280 mg) according to the same method as that of Example 330, the title compound (43 mg) was obtained as pale yellow amorphous powders.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07132547B2 |
| 출처 데이터셋 | uspto-grants-2006_11 |
| ORD ID | ord-65e9397d68d648e48a2a5e4cc5c1b2e9 |
| 출처 메모 | uspto-grants-2006_11 |