O-Phenylhydroxylamine → 1-(4-Fluorobenzyl)-N-phenoxy-1H-imidazo[4,5-c]pyridine-6-carboxamide

HRID 720546노트

반응식

HRID 720546 반응식
[F:1][C:2]1[CH:20]=[CH:19][C:5]([CH2:6][N:7]2[C:15]3[CH:14]=[C:13]([C:16]([OH:18])=O)[N:12]=[CH:11][C:10]=3[N:9]=[CH:8]2)=[CH:4][CH:3]=1.[O:21]([NH2:28])[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][N:7]2[C:15]3[CH:14]=[C:13]([C:16]([NH:28][O:21][C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=4)=[O:18])[N:12]=[CH:11][C:10]=3[N:9]=[CH:8]2)=[CH:19][CH:20]=1

참가 물질

3

반응물 2

HCID 2794249O-PhenylhydroxylamineHCID 218922171-(4-fluoro-benzyl)-1H-imidazo[4,5-c]pyridine-6-carboxylic acid

생성물 1

HCID 104063311-(4-Fluorobenzyl)-N-phenoxy-1H-imidazo[4,5-c]pyridine-6-carboxamide

실험 절차

The title compound can be prepared from 1-(4-fluoro-benzyl)-1H— imidazo[4,5-c]pyridine-6-carboxylic acid and N-phenoxyamine under the same conditions as those in step (c) of Example 1.

출처 및 근거

ORD 기록
ord-b8603ba82bbe413280b7eea2989ad1c0
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07135482B2

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