188814-26-8 → HCID 21895292, 화합물

반응식

[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]([NH:14][C:15]([O:17]CC2C3C=CC=CC=3C3C2=CC=CC=3)=O)[CH2:10][C:11]([OH:13])=[O:12])[CH:5]=[C:6]([Cl:8])[CH:7]=1.[N:32]1[CH:37]=[CH:36][CH:35]=[CH:34][C:33]=1[NH:38][CH2:39][CH2:40][O:41][C:42]([NH:44][CH2:45]C(O)=O)=[O:43]>>[Cl:8][C:6]1[CH:5]=[C:4]([CH:9]([NH:14][C:15](=[O:17])[CH2:45][NH:44][C:42]([O:41][CH2:40][CH2:39][NH:38][C:33]2[CH:34]=[CH:35][CH:36]=[CH:37][N:32]=2)=[O:43])[CH2:10][C:11]([OH:13])=[O:12])[CH:3]=[C:2]([Cl:1])[CH:7]=1

참가 물질

반응물 2

HCID 10551749188814-26-8

HCID 21895308HCID 21895308, 화합물

생성물 1

HCID 21895292HCID 21895292, 화합물

실험 절차

prepared by reaction of 3-(3,5-dichlorophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propionic acid with the solid phase polystyrene A OH (Rapp, Art. No. HA 1 400 00), is reacted with [2-(pyridin-2-ylamino)ethoxycarbonylamino]acetic acid and cleaved off from the support, giving 3-(3,5-dichlorophenyl)-3-{2-[2-(pyridin-2-ylamino)ethoxycarbonylamino]ethanoylamino}propionic acid.

출처 및 근거

ORD 기록: ord-6093d24be6d14867bc2e213fcba782ce
출처 데이터셋: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07135587B2

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