Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,4-Diaminobenzonitrile → 2-Hydroxyquinoxaline-6-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,4-Diaminobenzonitrile | HCID 737285 | — |
| 반응물 | Glyoxylic acid, monohydrate | HCID 15620607 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 생성물 | 2-Hydroxyquinoxaline-6-carbonitrile | HCID 45121730 | — |
반응 단계
To a stirred solution of 3,4-diaminobenzonitrile (5.00 g, 37.6 mmol) in 5% aq HCl (20 mL) was added glyoxilic acid monohydrate (4.32 g, 46.9 mmol). The mixture was stirred overnight at rt and filtered. The filter cake was washed with water and MeOH to afford 2-oxo-1,2-dihydroquinoxaline-6-carbonitrile as a grey solid which was used directly in the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08828985B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-f4d6d8765b134ec98904a66135422cd8 |
| 출처 메모 | uspto-grants-2014_09 |