2-Amino-3-nitro-5-cyclohexylmethyl-pyridine → 2-Amino-3-nitro-5-cyclohexylmethyl-pyridine

HRID 722055노트

반응식

HRID 722055 반응식
[NH2:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([CH2:11][CH:12]2[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]2)=[CH:4][N:3]=1>ClCCl.CO>[NH2:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([CH2:11][CH:12]2[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]2)=[CH:4][N:3]=1.[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][C:5]([CH2:11][CH:12]2[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]2)=[CH:4][N:3]=1

참가 물질

4

반응물 1

HCID 218827232-Amino-3-nitro-5-cyclohexylmethyl-pyridine

생성물 2

HCID 218827232-Amino-3-nitro-5-cyclohexylmethyl-pyridineHCID 21882760HCID 21882760, 화합물

시약·촉매·용매 1

HCID 21226129Dichloromethane methanol용매

실험 절차

Similiarly to Example C1, the hydrogenation of 0.365 g of 2-amino-3-nitro-5-cyclohexylmethyl-pyridine (starting material E2) gives 0.29 g of the title compound as a dark powder (after chromatography with dichloromethane/methanol 99:1). The mass spectrum shows the molecular peak MH+ at 205 Da.

출처 및 근거

ORD 기록
ord-f82e2bbfa90046c5b5d2ce8b79de1e5f
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07138399B2

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