Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-(3-Methoxy-4-nitrophenyl)-1,3,4-oxadiazol-2(3H)-one → 5-(4-Amino-3-methoxyphenyl)-1,3,4-oxadiazol-2(3H)-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-(3-Methoxy-4-nitrophenyl)-1,3,4-oxadiazol-2(3H)-one | HCID 21883906 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 5-(4-Amino-3-methoxyphenyl)-1,3,4-oxadiazol-2(3H)-one | HCID 21883858 | — |
반응 단계
Hydrogen was introduced under atmospheric pressure into the mixture of 550 mg of 5-(3-methoxy-4-nitrophenyl)-3H-[1,3,4]oxadiazol-2-one, 100 mg of Pd/C and 50 ml of THF up to the theoretical uptake. Afterwards, the catalyst was filtered off with suction and the mixture was concentrated to dryness under reduced pressure.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07138414B2 |
| 출처 데이터셋 | uspto-grants-2006_11 |
| ORD ID | ord-d939b21e53a944c3aa5ddfdff4b7cc5a |
| 출처 메모 | uspto-grants-2006_11 |