HCID 2758791, 화합물 → HCID 21884080, 화합물
반응식
[NH2:1][CH:2]([C:9]1[CH:14]=[C:13]([Cl:15])[CH:12]=[C:11]([Cl:16])[CH:10]=1)[CH2:3][C:4]([O:6][CH2:7][CH3:8])=[O:5].[CH2:17]([O:24][CH2:25][CH:26]([NH:30][C:31]([O:33][CH2:34][CH2:35][NH:36][C:37]1[CH:42]=[CH:41][CH:40]=[C:39]([CH3:43])[N:38]=1)=[O:32])[C:27](O)=[O:28])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH2:17]([O:24][CH2:25][CH:26]([NH:30][C:31]([O:33][CH2:34][CH2:35][NH:36][C:37]1[CH:42]=[CH:41][CH:40]=[C:39]([CH3:43])[N:38]=1)=[O:32])[C:27]([NH:1][CH:2]([C:9]1[CH:10]=[C:11]([Cl:16])[CH:12]=[C:13]([Cl:15])[CH:14]=1)[CH2:3][C:4]([O:6][CH2:7][CH3:8])=[O:5])=[O:28])[C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1참가 물질
3
실험 절차
Analogously to Example 2, ethyl 3-amino-3-(3,5-dichlorophenyl)propionate is reacted with 3-benzyloxy-2-[2-(6-methylpyridin-2-ylamino)ethoxycarbonylamino]propionic acid and purified by chromatography, giving ethyl 3-{3-benzyloxy-2-[2-(6-methylpyridin-2-ylamino)ethoxycarbonylamino]-propanoylamino}-3-(3,5-dichlorophenyl)propionate, RT 1.765 min, FAB-MS (M+H)+ 618.
후처리
- custompurified by chromatography
출처 및 근거
- ORD 기록
- ord-14a8463e1a384417aacba2a2669849e6
- 출처 데이터셋
- uspto-grants-2006_11