3-(CHLOROMETHYL)-2-METHYLPYRIDINE HYDROCHLORIDE → HCID 25235364, 화합물
반응식
[CH2:1]([C@:3]12[C:16]3[C:11](=[CH:12][C:13]([OH:17])=[CH:14][CH:15]=3)[CH2:10][CH2:9][C@@H:8]1[CH2:7][C@:6]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)([OH:18])[C@@H:5]([OH:25])[CH2:4]2)[CH3:2].Cl.Cl[CH2:28][C:29]1[C:30]([CH3:35])=[N:31][CH:32]=[CH:33][CH:34]=1>>[CH2:1]([C@:3]12[C:16]3[C:11](=[CH:12][C:13]([O:17][CH2:28][C:29]4[C:30]([CH3:35])=[N:31][CH:32]=[CH:33][CH:34]=4)=[CH:14][CH:15]=3)[CH2:10][CH2:9][C@@H:8]1[CH2:7][C@:6]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)([OH:18])[C@@H:5]([OH:25])[CH2:4]2)[CH3:2]참가 물질
3
실험 절차
The title compound was prepared starting from the title product of Example 16 and 3-chloromethyl-2 methylpyridine hydrochloride using a procedure analogous to that outlined for Example 2. Product was isolated by flash chromatography eluting with 30% methylene chloride in ethyl acetate. Mass spectrum: m/e 444 (M+1).
후처리
- customProduct was isolated by flash chromatography
- washeluting with 30% methylene chloride in ethyl acetate
출처 및 근거
- ORD 기록
- ord-0cf1ebfce2234f8283e68f1175ac784d