Sodium ethoxide → 2-(5-Nitro-2-ethoxyphenyl)-5-phenylbenzoxazole
반응식
[N+:1]([C:4]1[CH:5]=[CH:6][C:7](F)=[C:8]([C:10]2[O:11][C:12]3[CH:18]=[CH:17][C:16]([C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=4)=[CH:15][C:13]=3[N:14]=2)[CH:9]=1)([O-:3])=[O:2].[O-:26][CH2:27][CH3:28].[Na+]>>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([O:26][CH2:27][CH3:28])=[C:8]([C:10]2[O:11][C:12]3[CH:18]=[CH:17][C:16]([C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=4)=[CH:15][C:13]=3[N:14]=2)[CH:9]=1)([O-:3])=[O:2]참가 물질
3
실험 절차
Prepared by the method of Example 40a), from 2-(5-nitro-2-fluorophenyl)-5-phenylbenzoxazole (200 mg, 0.60 mmol) and sodium ethoxide (41 mg, 0.61 mmol) the subtitle compound was obtained (197 mg, 91%). 1H NMR (DMSO) δ 8.92(d, 1H), 8.51(dd, 1H), 8.18(s, 1H), 7.95(d, 1H), 7.83(d, 2H), 7.56(t, 3H), 7.47(t, 3H), 4.50(q, 2H), 1.57(t, 3H).
출처 및 근거
- ORD 기록
- ord-ef2930e60d9c4601802f454f0e231626
- 출처 데이터셋
- uspto-grants-2006_11
- 특허 번호
- US07138425B2