2-Amino-4-Bromophenol → N-(2-hydroxy-5-bromophenyl)-2-fluoro-5-nitrobenzamide

HRID 722569노트

반응식

HRID 722569 반응식
[NH2:1][C:2]1[CH:7]=[C:6]([Br:8])[CH:5]=[CH:4][C:3]=1[OH:9].[F:10][C:11]1[CH:19]=[CH:18][C:17]([N+:20]([O-:22])=[O:21])=[CH:16][C:12]=1[C:13](Cl)=[O:14]>>[OH:9][C:3]1[CH:4]=[CH:5][C:6]([Br:8])=[CH:7][C:2]=1[NH:1][C:13](=[O:14])[C:12]1[CH:16]=[C:17]([N+:20]([O-:22])=[O:21])[CH:18]=[CH:19][C:11]=1[F:10]

참가 물질

3

반응물 2

HCID 3518402-Amino-4-BromophenolHCID 109765702-Fluoro-5-nitrobenzoyl chloride

생성물 1

HCID 21884381N-(2-hydroxy-5-bromophenyl)-2-fluoro-5-nitrobenzamide

실험 절차

Prepared by the method of Example 15a), from 2-amino-4-bromophenol (752 mg, 4.0 mmol) and 2-fluoro-5-nitrobenzoyl chloride (814 g, 4.0 mmol) the subtitle compound was obtained. The product was used directly in the next step without purification.

출처 및 근거

ORD 기록
ord-16a5f72709cc4e4fb24bb6e0abddb3e4
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07138425B2

반응 노트

불러오는 중…