Trimellitic anhydride → HCID 21884393, 화합물

반응식

[NH2:1][C:2]1[CH:3]=[C:4]([C:12]2[O:13][C:14]3[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][C:15]=3[N:16]=2)[C:5]([NH:8][CH2:9][CH2:10][CH3:11])=[CH:6][CH:7]=1.[CH:22]1[C:27]([C:28]([OH:30])=[O:29])=[CH:26][C:25]2[C:31]([O:33][C:34](=O)[C:24]=2[CH:23]=1)=[O:32]>>[CH3:21][C:18]1[CH:19]=[CH:20][C:14]2[O:13][C:12]([C:4]3[CH:3]=[C:2]([N:1]4[C:31](=[O:32])[C:25]5[C:24](=[CH:23][CH:22]=[C:27]([C:28]([OH:30])=[O:29])[CH:26]=5)[C:34]4=[O:33])[CH:7]=[CH:6][C:5]=3[NH:8][CH2:9][CH2:10][CH3:11])=[N:16][C:15]=2[CH:17]=1

참가 물질

반응물 2

HCID 11089Trimellitic anhydride

HCID 21884601HCID 21884601, 화합물

생성물 1

HCID 21884393HCID 21884393, 화합물

실험 절차

Prepared by the method of Example 15f), from 2-(3-amino-6-propylaminophenyl)-5-methylbenzoxazole (112 mg, 0.4 mmol) and 1,2,4-benzenetricarboxylic anhydride (96 mg, 0.5 mmol) the title compound was obtained (92 mg, 50%). 1H NMR (DMSO) δ 8.60(t, 1H), 8.41(d, 1H), 8.29(s, 1H), 8.08(m, 2H), 7.54(d, 1H), 7.45(d, 1H), 7.30(t, 1H), 7.22(d, 1H), 6.99(d, 1H), 3.34(m, 2H), 2.59(s, 3H), 1.79(m, 2H), 1.12(t, 3H). MS 454.1 m/z (M−H)−.

출처 및 근거

ORD 기록: ord-920d613ab02740beaf9c1e198a8f71f9
출처 데이터셋: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07138425B2

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