Trimellitic anhydride → HCID 21884556, 화합물

반응식

[NH2:1][C:2]1[CH:3]=[C:4]([C:10]2[O:11][C:12]3[CH:18]=[CH:17][C:16]([C:19]4[CH:24]=[CH:23][C:22]([Cl:25])=[C:21]([CH3:26])[CH:20]=4)=[CH:15][C:13]=3[N:14]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[CH:27]1[C:32]([C:33]([OH:35])=[O:34])=[CH:31][C:30]2[C:36]([O:38][C:39](=O)[C:29]=2[CH:28]=1)=[O:37]>>[CH3:9][O:8][C:7]1[CH:6]=[CH:5][C:4]([C:10]2[O:11][C:12]3[CH:18]=[CH:17][C:16]([C:19]4[CH:24]=[CH:23][C:22]([Cl:25])=[C:21]([CH3:26])[CH:20]=4)=[CH:15][C:13]=3[N:14]=2)=[CH:3][C:2]=1[N:1]1[C:36](=[O:37])[C:30]2[C:29](=[CH:28][CH:27]=[C:32]([C:33]([OH:35])=[O:34])[CH:31]=2)[C:39]1=[O:38]

참가 물질

반응물 2

HCID 11089Trimellitic anhydride

HCID 21884433HCID 21884433, 화합물

생성물 1

HCID 21884556HCID 21884556, 화합물

실험 절차

Prepared by the method of Example 1b), from 2-(3-amino-4-methoxyphenyl)-5-(3-methyl-4-chlorophenyl)benzoxazole (79 mg, 0.22 mmol) and 1,2,4-benzenetricarboxylic anhydride (42 mg, 0.22 mmol) the title compound was obtained (22 mg, 19%). 1H NMR (DMSO) δ 8.55(dd, 1H), 8.44(m, 3H), 8.22(d, 1H), 8.14(m, 1H), 7.90(m, 3H), 7.65(m, 3H), 4.00(s, 3H), 2.45(s, 3H). MS 527 m/z (M+H)+.

출처 및 근거

ORD 기록: ord-9a34773d6f504487ae4a5acaee81c04d
출처 데이터셋: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07138425B2

반응 노트

불러오는 중…