Benzo(B)Thiophene-2-Boronic Acid → HCID 21884571, 화합물

반응식

[N+:1]([C:4]1[CH:5]=[C:6]([C:12]2[O:13][C:14]3[CH:20]=[CH:19][C:18](Br)=[CH:17][C:15]=3[N:16]=2)[C:7]([O:10][CH3:11])=[CH:8][CH:9]=1)([O-:3])=[O:2].[S:22]1[C:26]2[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=2[CH:24]=[C:23]1B(O)O>>[N+:1]([C:4]1[CH:5]=[C:6]([C:12]2[O:13][C:14]3[CH:20]=[CH:19][C:18]([C:23]4[S:22][C:26]5[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=5[CH:24]=4)=[CH:17][C:15]=3[N:16]=2)[C:7]([O:10][CH3:11])=[CH:8][CH:9]=1)([O-:3])=[O:2]

참가 물질

반응물 2

HCID 2359Benzo(B)Thiophene-2-Boronic Acid

HCID 21884587HCID 21884587, 화합물

생성물 1

HCID 21884571HCID 21884571, 화합물

실험 절차

Prepared by the method of Example 15d), from 2-(3-nitro-6-methoxyphenyl)-5-bromobenzoxazole (400 mg, 1.14 mmol) and benzothiophene-2-boronic acid (306 mg, 1.71 mmol) the subtitle compound was obtained (569 mg, 123%). The product was used directly in the next step without purification.

출처 및 근거

ORD 기록: ord-255b0c8539eb4db08b4c5b9cd3843eae
출처 데이터셋: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07138425B2

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