Sulfuric Acid → Glyceryl methacrylate

HRID 722666

반응식

HRID 722666 반응식
[CH2:1]([O:5][C:6](=[O:10])[C:7]([CH3:9])=[CH2:8])[CH:2]1[O:4][CH2:3]1.C[O:12]C1C=CC(O)=CC=1.S(=O)(=O)(O)O.S([O-])([O-])(=O)=O.[Na+].[Na+]>O>[C:6]([O:5][CH2:1][CH:2]([CH2:3][OH:12])[OH:4])(=[O:10])[C:7]([CH3:9])=[CH2:8]

참가 물질

6

반응물 4

HCID 1118Sulfuric AcidHCID 7837Glycidyl methacrylateHCID 90154-MethoxyphenolHCID 24436Sodium Sulfate

생성물 1

HCID 65442Glyceryl methacrylate수율 80%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Into a two phase mixture of 86 g (0.6 mol) of comercial glycidylmethacrylate containing 200 ppm of MEHQ and 500 ml of water is added 2 ml of concentrated sulfuric acid at ambient temperature. After stirring approximately 18 hours, the mixture appeared as a clear homogenous solution. To the resultant solution is added sufficient sodium sulfate to cause separation of an oil. The 2 phase mixture is extracted sequentially with 5 portions of 150 ml each of chloroform and the combined chloroform extracts are dried over solid sodium sulfate. After filtering the solid sodium sulfate, the solvent is removed by evaporation to give 77 g (80%) of glycerol mono-methacrylate as a clear colorless oil. The monomer can be used without further purification or can be further purified by chromatography to separate trace amounts of glycerol di-methacrylate.

후처리

  1. customseparation of an oil
  2. extractionThe 2 phase mixture is extracted sequentially with 5 portions of 150 ml each of chloroform
  3. dry with materialthe combined chloroform extracts are dried over solid sodium sulfate
  4. filtrationAfter filtering the solid sodium sulfate
  5. customthe solvent is removed by evaporation

출처 및 근거

ORD 기록
ord-3c76a2f843a94fe98f011185866b09ce
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07138457B2

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