2-(Bromomethyl)pyridine → Carbamic acid 1-{3-[4-(pyridin-2-ylmethoxy)-phenyl]-isoxazol-5-yl}-ethyl ester

HRID 72335

반응식

HRID 72335 반응식
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[CH:19]=[C:18]([CH:20]([O:22][C:23](=[O:25])[NH2:24])[CH3:21])[O:17][N:16]=2)=[CH:11][CH:10]=1)[C:2]1C=[CH:6][CH:5]=[CH:4][CH:3]=1.BrCC1C=CC=C[N:29]=1>>[N:29]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:1][O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[CH:19]=[C:18]([CH:20]([O:22][C:23](=[O:25])[NH2:24])[CH3:21])[O:17][N:16]=2)=[CH:11][CH:10]=1

참가 물질

3

실험 절차

The compound was synthesized using carbamic acid 1-[3-(4-benzyloxy-phenyl)-isoxazol-5-yl]-ethyl ester of example 117 in the same manner as in Example 10 by debenzylation following reaction with 2-bromomethylpyridine.

후처리

  1. customThe compound was synthesized

출처 및 근거

ORD 기록
ord-3cae1a8ecd6e471b98a7d5133f42f89e
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08828992B2

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