1H-1,2,4-Triazole → 1-(4-Cyclopentyloxyphenyl)-3-[4-(2-[1,2,4]triazol-4-ylethoxy)phenyl]-1,3-dihydroimidazol-2-one

HRID 723370

반응식

HRID 723370 반응식
Br[CH2:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([N:11]2[CH:15]=[CH:14][N:13]([C:16]3[CH:21]=[CH:20][C:19]([O:22][CH:23]4[CH2:27][CH2:26][CH2:25][CH2:24]4)=[CH:18][CH:17]=3)[C:12]2=[O:28])=[CH:7][CH:6]=1.[NH:29]1[CH:33]=[N:32][CH:31]=[N:30]1>>[CH:23]1([O:22][C:19]2[CH:18]=[CH:17][C:16]([N:13]3[CH:14]=[CH:15][N:11]([C:8]4[CH:7]=[CH:6][C:5]([O:4][CH2:3][CH2:2][N:32]5[CH:31]=[N:30][N:29]=[CH:33]5)=[CH:10][CH:9]=4)[C:12]3=[O:28])=[CH:21][CH:20]=2)[CH2:24][CH2:25][CH2:26][CH2:27]1

참가 물질

3

반응물 2

HCID 92571H-1,2,4-TriazoleHCID 218733301-[4-(2-Bromoethoxy)phenyl]-3-(4-cyclopentyloxyphenyl)-1,3-dihydroimidazol-2-one

생성물 1

HCID 218733211-(4-Cyclopentyloxyphenyl)-3-[4-(2-[1,2,4]triazol-4-ylethoxy)phenyl]-1,3-dihydroimidazol-2-one

실험 절차

1-[4-(2-Bromoethoxy)phenyl]-3-(4-cyclopentyloxyphenyl)-1,3-dihydroimidazol-2-one was reacted with 1,2,4-triazole as described in example 5. The product with the molecular weight of 431.50 (C24H25N5O3); MS (ESI): 432 ([M+H]+) was obtained in this way.

후처리

  1. customMS (ESI): 432 ([M+H]+) was obtained in this way

출처 및 근거

ORD 기록
ord-9cdb71c81e214bcd9b51e4e4364b17b7
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07141561B2

연결된 노트

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