Piperidin-1-yl-acetic acid → HCID 21873421, 화합물

HRID 723375

반응식

HRID 723375 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:12]=[CH:11][N:10]([C:13]3[CH:18]=[CH:17][C:16]([O:19][C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)=[CH:15][CH:14]=3)[C:9]2=[O:26])=[CH:4][CH:3]=1.[N:27]1([CH2:33][C:34](O)=[O:35])[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]1>>[O:26]=[C:9]1[N:10]([C:13]2[CH:18]=[CH:17][C:16]([O:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[CH:15][CH:14]=2)[CH:11]=[CH:12][N:8]1[C:5]1[CH:4]=[CH:3][C:2]([NH:1][C:34](=[O:35])[CH2:33][N:27]2[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]2)=[CH:7][CH:6]=1

참가 물질

3

반응물 2

HCID 201097Piperidin-1-yl-acetic acidHCID 102468281-(4-Aminophenyl)-3-(4-phenoxyphenyl)-1,3-dihydroimidazol-2-one

생성물 1

HCID 21873421HCID 21873421, 화합물

실험 절차

1-(4-Aminophenyl)-3-(4-phenoxyphenyl)-1,3-dihydroimidazol-2-one was reacted with piperidin-1-ylacetic acid as described in example 217. The product with the molecular weight of 468.56 (C28H28N4O3); MS (ESI): 469 ([M+H]+) was obtained as hydrotrifluoroacetate in this way.

후처리

  1. customMS (ESI): 469 ([M+H]+) was obtained as hydrotrifluoroacetate in this way

출처 및 근거

ORD 기록
ord-5a55c84b3b724d5c962033c2618d99df
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07141561B2

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