Isopropanol → HCID 59858068, 화합물

HRID 723743

반응식

HRID 723743 반응식
[CH:1]([OH:4])([CH3:3])[CH3:2].[CH3:5][C:6]1[O:7][C:8]([CH3:14])=[CH:9][C:10]=1[C:11](Cl)=[O:12]>C(Cl)Cl>[CH:1]([O:4][C:11]([C:10]1[CH:9]=[C:8]([CH3:14])[O:7][C:6]=1[CH3:5])=[O:12])([CH3:3])[CH3:2]

참가 물질

4

반응물 2

HCID 3776IsopropanolHCID 27348042,5-Dimethyl-3-furoyl Chloride

생성물 1

HCID 59858068HCID 59858068, 화합물수율 96%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Isopropanol (5 ml) was added to a solution of 2,5-dimethylfuran-3-carbonylchloride (1.64 g; 10.3 mmol) in 15 ml of methylene chloride at rt. After allowing the reaction mixture to stand at rt for 30 mins, the volatiles were removed in vacuo and the residue was co-evaporated from isopropanol to afford compound 865A (1.8 g, 96%) as a light amber liquid. 1HNMR (CDCl3): δ 1,30 (d, j=6.5 Hz, 6H), 2.23 (s, 3H), 2.52 (s, 3H), 5.14 (m, 1H), 6.21 (s, 1H).

후처리

  1. customthe volatiles were removed in vacuo

출처 및 근거

ORD 기록
ord-1ee69266ac0e440488fbee11e75fed84
출처 데이터셋
uspto-grants-2006_11
특허 번호
US07141578B2

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