Dichloromethane → tert-butyl (1S)-1-[4-(2-tert-butyl-1,1-dioxido-3-oxo-2,3-dihydroisothiazol-5-yl)benzyl]-2-hydroxyethylcarbamate

반응식

[OH:1][CH2:2][C@H:3]([NH:20][C:21](=[O:27])[O:22][C:23]([CH3:26])([CH3:25])[CH3:24])[CH2:4][C:5]1[CH:10]=[CH:9][C:8](B2OC(C)(C)C(C)(C)O2)=[CH:7][CH:6]=1.[C:28]([N:32]1[C:36](=[O:37])[CH:35]=[C:34](Cl)[S:33]1(=[O:40])=[O:39])([CH3:31])([CH3:30])[CH3:29].C(=O)([O-])[O-].[K+].[K+].ClCCl>O1CCOCC1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>[C:28]([N:32]1[C:36](=[O:37])[CH:35]=[C:34]([C:8]2[CH:7]=[CH:6][C:5]([CH2:4][C@H:3]([NH:20][C:21](=[O:27])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:2][OH:1])=[CH:10][CH:9]=2)[S:33]1(=[O:39])=[O:40])([CH3:31])([CH3:29])[CH3:30]