Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Chlorophenol → 2-(3-(3-Chlorophenoxy)azetidin-1-yl)-5-(trifluoromethyl)nicotinic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Chlorophenol | HCID 7933 | — |
| 반응물 | Methyl 2-(3-((methylsulfonyl)oxy)azetidin-1-yl)-5-(trifluoromethyl)nicotinate | HCID 86697871 | — |
| 생성물 | 2-(3-(3-Chlorophenoxy)azetidin-1-yl)-5-(trifluoromethyl)nicotinic acid | HCID 67958317 | 88.4% |
반응 단계
The title compound (D124) (85 mg) was prepared according to the experimental procedure described in Description 103A starting from methyl 2-(3-((methylsulfonyl)oxy)azetidin-1-yl)-5-(trifluoromethyl)nicotinate (D68) (100 mg, 0.258 mmol) and 3-Chlorophenol (0.035 ml, 0.338 mmol).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08828987B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-12374997667c4aee9c09d06757e67123 |
| 출처 메모 | uspto-grants-2014_09 |