Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Fluorophenol → 5-Fluoro-2-(3-(3-fluorophenoxy)azetidin-1-yl)nicotinic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Fluorophenol | HCID 9743 | — |
| 반응물 | Methyl 5-fluoro-2-(3-((methylsulfonyl)oxy)azetidin-1-yl)nicotinate | HCID 86697878 | — |
| 생성물 | 5-Fluoro-2-(3-(3-fluorophenoxy)azetidin-1-yl)nicotinic acid | HCID 67958637 | 119.5% |
반응 단계
The title compound (D132) (108 mg) was prepared according to the experimental procedure described in Description 115 starting from methyl 5-fluoro-2-(3-((methylsulfonyl)oxy)azetidin-1-yl)nicotinate (D71) (90 mg, 0.295 mmol) and 3-Fluorophenol (0.029 ml, 0.295 mmol).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08828987B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-c613aafd2f95412e82b2c5be69c870a5 |
| 출처 메모 | uspto-grants-2014_09 |