Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Toluenesulfonic acid → 3-Ethoxycarbonyl-3-(4-nitrophenyl)propionic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Toluenesulfonic acid | HCID 6101 | — |
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | (4-Nitrophenyl)acetate | HCID 6931101 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 3-Ethoxycarbonyl-3-(4-nitrophenyl)propionic acid | HCID 11807640 | — |
반응 단계
Following a similar procedure to that described in reference example 7b, but starting fromethyl 4-nitrophenylacetate instead of ethyl diphenylacetate, and hydrolizing then the tert-butyl ester using p-toluenesulfonic acid in benzene at reflux instead of using trifluoroacetic acid, the title compound was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05705504 |
| 출처 데이터셋 | uspto-grants-1998_01 |
| ORD ID | ord-c2c552ccf12b44bfa6feed885d81df99 |
| 출처 메모 | uspto-grants-1998_01 |